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USA products for Neuro Monitoring

 

Cerebral tissue monitoring system According to the CDC, stroke is the no. 3 cause of death in the US affecting more than 700,000 individuals annually. Subarachnoid Hemorrhage (SAH) represents only about 7 percent of all strokes, but has a fatality rate of more than 50 percent. Of the survivors, approximately half will suffer permanent disability.

One of the most common complications after a stroke is vasospasm. Approximately one third of spontaneous SAH’s and 30-60% of traumatic bleeds are followed by vasospasm, or blood vessel constriction. Early signs of vasospasm and secondary ischemia following severe head injuries are key indicators for guiding therapy and ultimately saving lives.

Ischemia resulting from brain trauma and hemorrhage has been found to cause profound changes in levels of glucose, lactate, and pyruvate in the interstitial fluid. CMA’s cerebral tissue monitoring system monitors these levels continuously to help evaluate the effect of therapeutic interventions as well as detect secondary ischemic insults. Recent studies have concluded that changes in energy substrates and ischemic metabolites: 

  • Precede the onset of symptomatic vasospasm in SAH 1,2
  • In TBI, allow for the observation of the consequences of anemic hypoxia several hours before the detoration was detected by ICP/CPP 3
  • May be predicitive of outcome in TBI 4

When used in conjunction with existing techniques such as ICP and pO2, CMA’s cerebral tissue monitoring system can provide valuable information on the metabolic status of cerebral tissue.

To view the 510(k) clearance  510K.pdf

References

  1. Nilsson O, Brandt L, Ungerstedt U, Säveland H, Bedside Detection of Brain Ischemia Using Intracerebral Microdialysis: Subarachnoid Hemorrhage and Delayed Ischemic Deterioration, Neurosurgery 45:1176–1185, 1999.
  2. Sarrafzadeh, A., Sakowitz, O, Kiening, K., Benndorf, G., Lanksch, W, and Unterberg, A, Bedside Microdialysis: A tool to monitor cerebral metabolism in subarachnoid hemorrhage patients, Critical Care Medicine, 2002, Vol. 30, No. 5, 1062-1070.
  3. Stahl, N., Mellergard, P., Hallstrom, A., Ungerstedt, U., and Nordstrom, C. H., Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions, Acta Anesthesiol Scand, 2001; 45; 977-985.
  4. Hutchinson, P., Al-Rawi, P., O'Connell, M., Gupta, A., Maskell, L., Hutchinson, D., Pickard, J., Kirkpatrick, P., On-Line monitoring of substrate delivery and brain metabolism in head injury, Acta Neurochir, 2000, (Suppl) 76: 431-435.

US products list

CMA 70 Brain Microdialysis Catheter

CMA 70 Microdialysis Bolt Catheter
CMA 106 Microdialysis Pump

ISCUS Clinical Microdialysis Analyzer
Microvials

Control Samples
Perfusion Fluid CNS

 

CMA Microdialysis Inc.   73 Princeton Street, North Chelmsford, MA 01863, USA   Phone 800 440 4980, +1  978 251 1940
Fax +1-978 251 1950   E-mail CMA.USA@microdialysis.com