General metabolism

Continuous monitoring of small substances without removing any blood

Microdialysis allows frequent sampling of substances involved in Glucose and lipid metabolism without removing any blood. This makes it possible to perform  research on continuous monitoring of Glucose, Lactate, Pyruvate, and Glycerol in newborn babies (Baumeister et al. Pediatrics 2001;108;1187-1192) , diabetic patients (Rajamand N et al. Diabetes, Obesity and Metabolism, 2005, 7, 525–535) and in critically ill septic patients (Levy B et al. Lancet 2005; 365: 871–75).

Microdialysis in resting skeletal muscle

 The use of microdialysis in resting skeletal muscle has become an important technique for mechanistic studies in human metabolism and nutrition. (Henriksson J et al Proc Nutr Soc. 1999 Nov;58).

Intravenous Microdialysis

Intravenous Microdialysis is an enhancement of the conventional interstitial Microdialysis technology. It enables frequent or continuous analyzes of endogenous substances or drugs without any blood loss or discomfort for the patient. An optimized design allows for continuous monitoring of smaller substances such as glucose, lactate, pyruvate and urea in blood and is suitable for several purposes; from pharmacokinetic studies to monitoring of diabetic patients. (Dizar N et al. Dep. of Neurology, Linköping University
Hospital)