Bibliography on Cutaneous Microdialysis

Experimental thermal lesions induce beta-thromboglobulin release from activated platelets.
Blunk JA, Sauerstein K, Schmelz M.
Eur J Pain. 2010 May 24. [Epub ahead of print]

VIP/PACAP Receptor Mediation of Cutaneous Active Vasodilation During Heat Stress in Humans.
Kellogg DL Jr, Zhao JL, Wu Y, Johnson JM.
J Appl Physiol. 2010 Apr 15. [Epub ahead of print]

Systemic low-dose aspirin and clopidogrel independently attenuate reflex cutaneous vasodilation in middle-aged humans.
Holowatz LA, Jennings JD, Lang JA, Kenney WL.
J Appl Physiol. 2010 Jun;108(6):1575-81. Epub 2010 Apr 1.

Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human
forearm skin.
Leis S, Meyer N, Bickel A, Schick CH, Krüger S, Schmelz M, Birklein F.
Pain Med. 2010 May;11(5):774-80. Epub 2010 Mar 1.


Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction.
Lang JA, Holowatz LA, Kenney WL.
J Physiol. 2010 Apr 15;588(Pt 8):1361-8. Epub 2010 Feb 22.

Nitric oxide synthase inhibition attenuates cutaneous vasodilation during postmenopausal hot flash episodes.
Hubing KA, Wingo JE, Brothers RM, Del Coso J, Low DA, Crandall CG.
Menopause. 2010 May 24. [Epub ahead of print]


Microdialysis Sampling for Investigations of Bioavailability and Bioequivalence of Topically Administered Drugs: Current State and Future Perspectives.
Holmgaard R, Nielsen JB, Benfeldt E.
Skin Pharmacol Physiol. 2010 May 18;23(5):225-243. [Epub ahead of print]

Intradermal Administration of ATP Does Not Mitigate Tyramine-Stimulated Vasoconstriction in Human Skin.
Wingo JE, Brothers RM, Del Coso J, Crandall CG.
Am J Physiol Regul Integr Comp Physiol. 2010 Mar 17. [Epub ahead of print]

Thoracoscopic Sympathectomy at the T2 or T3 Level Facilitates Bradykinin-Induced Protein Extravasation in Human Forearm Skin.
Leis S, Meyer N, Bickel A, Schick CH, Krüger S, Schmelz M, Birklein F.
Pain Med. 2010 Mar 1. [Epub ahead of print]

Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction.
Lang JA, Holowatz LA, Kenney WL.
J Physiol. 2010 Feb 22. [Epub ahead of print]

Local ascorbate administration inhibits the adrenergic vasoconstrictor response to local cooling in the human skin.
Yamazaki F.
J Appl Physiol. 2010 Feb;108(2):328-33. Epub 2009 Dec 10.

Mechanical but not painful electrical stimuli trigger TNF alpha release in human skin.
Eberle T, Doganci B, Krämer H, Fechir M, Wagner I, Sommer C, Birklein F.
Exp Neurol. 2010 Jan;221(1):246-50. Epub 2009 Nov 18.

Local sensory nerve control of skin blood flow during local warming in type 2 diabetes mellitus.
Strom NA, Sawyer JR, Roberts SK, Kingsley-Berg SM, Charkoudian N.
J Appl Physiol. 2010 Feb;108(2):293-7. Epub 2009 Dec 3

Comparison of NO contents and cutaneous electric conduction quantity at the acupoints and the non-acupoints
[Article in Chinese]
Ben H, Li L, Gao XY, He W, Rong PJ.
Zhen Ci Yan Jiu. 2009 Dec;34(6):383-6, 392.

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation.
Cohen J, Deans R, Dalley A, Lipman J, Roberts MS, Venkatesh B.
Crit Care. 2009;13(6):R189. Epub 2009 Nov 27.

Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling.
Lang JA, Jennings JD, Holowatz LA, Kenney WL.
Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1792-7. Epub 2009 Aug 28.

Roles of nitric oxide synthase isoforms in cutaneous vasodilation induced by local warming of the skin and whole body heat stress in humans.
Kellogg DL Jr, Zhao JL, Wu Y.
J Appl Physiol. 2009 Nov;107(5):1438-44. Epub 2009 Sep 10.

Rapid UPLC-MS/MS method for the determination of ketoprofen in human dermal microdialysis samples.
Tettey-Amlalo RN, Kanfer I.
J Pharm Biomed Anal. 2009 Nov 1;50(4):580-6. Epub 2008 Oct 10.

Botulinum toxin abolishes sweating via impaired sweat gland responsiveness to exogenous acetylcholine.
Shibasaki M, Davis SL, Cui J, Low DA, Keller DM, Crandall CG.
Br J Dermatol. 2009 Oct;161(4):757-61. Epub 2009 Apr 22.
 

High fosfomycin concentrations in bone and peripheral soft tissue in diabetic patients presenting with bacterial foot infection.
Schintler MV, Traunmüller F, Metzler J, Kreuzwirt G, Spendel S, Mauric O, Popovic M, Scharnagl E, Joukhadar C.
J Antimicrob Chemother. 2009 Sep;64(3):574-8. Epub 2009 Jul 3.

Impact of adult atopic dermatitis on topical drug penetration: assessment by cutaneous microdialysis and tape stripping.
Garcia Ortiz P, Hansen SH, Shah VP, Menné T, Benfeldt E.
Acta Derm Venereol. 2009;89(1):33-8.

Ketorolac alters blood flow during normothermia but not during hyperthermia in middle aged human skin.
Holowatz LA, Jennings JD, Lang JA, Kenney WL.
J Appl Physiol. 2009 Aug 6. [Epub ahead of print]

Local tetrahydrobiopterin administration augments cutaneous vasoconstriction in aged humans.
Lang JA, Holowatz LA, Kenney WL.
J Physiol. 2009 Aug 1;587(Pt 15):3967-74. Epub 2009 Jun 2

Sitting can cause ischaemia in the subcutaneous tissue of the buttocks, which implicates multilayer tissue damage in the development of pressure ulcers.
Thorfinn J, Sjoberg F, Lidman D.
Scand J Plast Reconstr Surg Hand Surg. 2009;43(2):82-9.

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.
Roberts JA, Kirkpatrick CM, Roberts MS, Robertson TA, Dalley AJ, Lipman J.
J Antimicrob Chemother. 2009 Jul;64(1):142-50. Epub 2009 Apr 27.

Neural and non-neural control of skin blood flow during isometric handgrip exercise in the heat stressed human.
Shibasaki M, Rasmussen P, Secher NH, Crandall CG.
J Physiol. 2009 May 1;587(Pt 9):2101-7. Epub 2009 Mar 23.

Soft Tissue Penetration of Ceftobiprole in Healthy Volunteers Determined by In Vivo Microdialysis.
Barbour A, Schmidt S, Sabarinath SN, Grant M, Seubert C, Skee D, Murthy B, Derendorf H.
Antimicrob Agents Chemother. 2009 Apr 13. [Epub ahead of print]

Botulinum toxin abolishes sweating via impaired sweat gland responsiveness to exogenous acetylcholine.
Shibasaki M, Davis SL, Cui J, Low DA, Keller DM, Crandall CG.
Br J Dermatol. 2009 Apr 22. [Epub ahead of print

Piperacillin penetration into tissue of critically ill patients with sepsis--bolus versus continuous administration?
Roberts JA, Roberts MS, Robertson TA, Dalley AJ, Lipman J.
Crit Care Med. 2009 Mar;37(3):926-33.

Histamine is not released in acute thermal injury in human skin in vivo: a microdialysis study.
Petersen LJ, Pedersen JL, Skov PS, Nielsen HJ, Kehlet H
Inflamm Res. 2009 Mar 6. [Epub ahead of print]
PMID: 19266263 [PubMed - as supplied by publisher]

Determining heat and mechanical pain threshold in inflamed skin of human subjects.
Angst MS, Tingle M, Phillips NG, Carvalho B.
J Vis Exp. 2009 Jan 14;(23). pii: 1092. doi: 10.3791/1092.

Tissue accumulation of cephalothin in burns: a comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers.
Dalley AJ, Lipman J, Deans R, Venkatesh B, Rudd M, Roberts MS, Cross SE.
Antimicrob Agents Chemother. 2009 Jan;53(1):210-5. Epub 2008 Oct 27.

Samuelsson A, Abdiu A, Wackenfors A, Sjöberg F.
Serotonin kinetics in patients with burn injuries: a comparison between the local and systemic responses measured by microdialysis-a pilot study.
Burns. 2008 Aug;34(5):617-22. Epub 2008 Jan 15.

Ortiz PG, Hansen SH, Shah VP, Menné T, Benfeldt E.
The effect of irritant dermatitis on cutaneous bioavailability of a metronidazole formulation, investigated by microdialysis and dermatopharmacokinetic method.
Contact Dermatitis. 2008 Jul;59(1):23-30. Epub 2008 Jun 1.

Angst MS, Clark JD, Carvalho B, Tingle M, Schmelz M, Yeomans DC.
Cytokine profile in human skin in response to experimental inflammation, noxious stimulation, and administration of a COX-inhibitor: A microdialysis study.
Pain. 2008 Apr 5.

Hodges GJ, Kosiba WA, Zhao K, Johnson JM Ph D.
The involvement of norepinephrine, neuropeptide Y and nitric oxide in the cutaneous vasodilator response to local heating in humans.
J Appl Physiol. 2008 May 15.

Kezic S.
Methods for measuring in-vivo percutaneous absorption in humans.
Hum Exp Toxicol. 2008 Apr; 27 ( 4 ): 289-95 .

Kim A, Suecof LA, Sutherland CA, Gao L, Kuti JL, Nicolau DP.
In vivo microdialysis study of the penetration of daptomycin into soft tissues in diabetic versus healthy volunteers.
Antimicrob Agents Chemother. 2008 Nov; 52 ( 11 ): 3941-6 . Epub 2008 Sep 8.

Medow MS, Glover JL, Stewart JM.
Nitric oxide and prostaglandin inhibition during acetylcholine-mediated cutaneous vasodilation in humans.
Microcirculation. 2008 Aug; 15 ( 6 ): 569-79 .

Mowbray M, McLintock S, Weerakoon R, Lomatschinsky N, Jones S, Rossi AG, Weller RB.
Enzyme-Independent NO Stores in Human Skin: Quantification and Influence of UV Radiation.
J Invest Dermatol. 2008 Sep 25.

Shibasaki M, Low DA, Davis SL, Crandall CG.
Nitric oxide inhibits cutaneous vasoconstriction to exogenous norepinephrine .
J Appl Physiol. 2008 Sep 18.

Sørensen LT, Jørgensen S, Petersen LJ, Hemmingsen U, Bülow J, Loft S, Gottrup F.
Acute Effects of Nicotine and Smoking on Blood Flow, Tissue Oxygen, and Aerobe Metabolism of the Skin and Subcutis
J Surg Res. 2008 Mar

Roberts JA, Roberts MS, Robertson TA, Cross SE, Lipman J
A novel way to investigate the effects of plasma exchange on antibiotic levels: use of microdialysis.
Int J Antimicrob Agents. 2008 Mar;31(3):240-4. Epub 2007 Dec 4.

Schmidt S, Banks R, Kumar V, Rand KH, Derendorf H.
Clinical microdialysis in skin and soft tissues: an update.
J Clin Pharmacol. 2008 Mar; 48 ( 3 ): 351-64 . Review.

Tettey-Amlalo RN, Kanfer I, Skinner MF, Benfeldt E, Verbeeck R.
Application of dermal microdialysis for the evaluation of bioequivalence of a ketoprofen topical gel.
Eur J Pharm Sci. 2008 Sep 20.

Clough GF, Jackson CL, Lee JJ, Jamal SC, Church MK.
What Can Microdialysis Tell Us About the Temporal and Spatial Generation of Cytokines in Allergen-Induced Responses in Human Skin In Vivo?
J Invest Dermatol . 2007 Jun 28;

Holowatz LA, Kenney WL.
Local ascorbate administration augments NO- and non-NO-dependent reflex cutaneous vasodilation in hypertensive humans.
Am J Physiol Heart Circ Physiol . 2007 Aug;293(2):H1090-6.

Klimowicz A, Farfal S, Bielecka-Grzela S.
Evaluation of skin penetration of topically applied drugs in humans by cutaneous microdialysis: acyclovir vs. salicylic acid.
J Clin Pharm Ther . 2007 Apr;32(2):143-8.

Lorenzo S, Minson C.
Human Cutaneous Reactive Hyperemia: Role of BKCa Channels and Sensory Nerves.
J Physiol . 2007 Sep 27;

Low DA, Shibasaki M, Davis SL, Keller DM, Crandall CG.
Does local heating induced nitric oxide production attenuate vasoconstrictor responsiveness to lower body negative pressure in human skin?
J Appl Physiol. 2007 Feb 1;

Medow MS, Taneja I, Stewart JM.
Cyclooxygenase and nitric oxide synthase dependence of cutaneous reactive hyperemia in humans.
Am J Physiol Heart Circ Physiol . 2007 Jul;293(1):H425-32.

Mowbray M, Tan X, Wheatley PS, Morris RE, Weller RB.
Topically Applied Nitric Oxide Induces T-Lymphocyte Infiltration in Human Skin, but Minimal Inflammation.
J Invest Dermatol . 2007 Oct 4;

Schlereth T, Schonefeld S, Birklein F, Kirkpatrick CJ, Wessler I.
In vivo release of non-neuronal acetylcholine from human skin by dermal microdialysis: Effects of sunlight, UV-A and tactile stimulus.
Life Sci. 2007 Jan 12;

Simmons GH, Minson CT, Cracowski JL, Halliwill JR.
Systemic hypoxia causes cutaneous vasodilation in healthy humans.
J Appl Physiol . 2007 Aug;103(2):608-15.

Thompson-Torgerson CS, Holowatz LA, Flavahan NA, Kenney WL.
Rho kinase-mediated local cold-induced cutaneous vasoconstriction is augmented in aged human skin.
Am J Physiol Heart Circ Physiol . 2007 Jul;293(1):H30-6.

Vávrová K, Hrabálek A, Mac-Mary S, Humbert P, Muret P.
Ceramide analogue 14S24 selectively recovers perturbed human skin barrier.
Br J Dermatol. 2007 Oct; 157 ( 4 ): 704-12 . Epub 2007 Aug 17.

Yamazaki F, Takahara K, Sone R, Johnson JM.
Influence of hyperoxia on skin vasomotor control in normothermic and heat-stressed humans.
J Appl Physiol. 2007 Dec; 103 ( 6 ): 2026-33 . Epub 2007 Sep 20.
 
Zheng H, Shi LF, Hu JH.
Assessment of in vitro and in vivo recovery of sinomenine using microdialysis.
Skin Res Technol. 2007 Aug; 13 ( 3 ): 323-9 .

Anderson CD.
Cutaneous microdialysis: is it worth the sweat?
J Invest Dermatol. 2006 Jun;126(6):1207-9.

Averbeck M, Gebhardt CA, Voigt S, Beilharz S, Anderegg U, Termeer CC, Sleeman JP, Simon JC.
Differential Regulation of Hyaluronan Metabolism in the Epidermal and Dermal Compartments of Human Skin by UVB Irradiation.
J Invest Dermatol. 2006 Nov 2;

Cracowski JL, Minson CT, Salvat-Melis M, Halliwill JR.
Methodological issues in the assessment of skin microvascular endothelial function in humans.
Trends Pharmacol Sci. 2006 Sep;27(9):503-8.

Farfal S , Klimowicz A , Bielecka-Grzela S .
Acyclovir concentrations in the skin of humans after a single oral dose assessed by in vivo cutaneous microdialysis.
Skin Res Technol. 2006 Nov;12(4):228-34

Hodges GJ, Zhao K, Kosiba WA, Johnson JM.
The involvement of nitric oxide in the cutaneous vasoconstrictor response to local cooling in humans.
J Physiol. 2006 Aug 1;574(Pt 3):849-57.

Holowatz LA, Thompson CS, Kenney WL.
Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin.
Am J Physiol Heart Circ Physiol. 2006 Aug 11;

Holowatz LA, Thompson CS, Kenney WL.
L-arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin.
J Physiol. 2006 May 4; [Epub ahead of print]

Houghton BL, Meendering JR, Wong BJ, Minson CT.
Nitric oxide and noradrenaline contribute to the temperature threshold of the axon reflex response to gradual local heating in human skin.
J Physiol. 2006 Feb 23;

Kramer HH, Schmidt K, Leis S, Schmelz M, Sommer C, Birklein F.
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.
Peptides. 2006 Jan 4;

McCord GR, Cracowski JL, Minson CT.
Prostanoids contribute to cutaneous active vasodilation in humans.
Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R596-602.

Morgan CJ, Friedmann PS, Church MK, Clough GF.
Cutaneous microdialysis as a novel means of continuously stimulating eccrine sweat glands in vivo.
J Invest Dermatol. 2006 Jun;126(6):1220-5

Samuelsson A, Steinwall I, Sjoberg F.
Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients.
Crit Care. 2006 Dec 13;10(6):R172

Shibasaki M, Davis SL, Cui J, Low DA, Keller DM, Durand S, Crandall CG.
Neurally mediated vasoconstriction is capable of decreasing skin blood flow during orthostasis in the heat-stressed human.
J Physiol. 2006 Sep 15;575(Pt 3):953-9.

Wong BJ, Minson CT.
Neurokinin-1 receptor desensitization attenuates cutaneous active vasodilatation in humans.
J Physiol. 2006 Dec 15;577(Pt 3):1043-51.

Adams F, Jordan J, Schaller K, Luft FC, Boschmann M.
Blood flow in subcutaneous adipose tissue depends on skin-fold thickness.
Horm Metab Res. 2005 Feb;37(2):68-73.

Schlereth T, Birklein F, Haack KA, Schiffmann S, Kilbinger H, Kirkpatrick CJ, Wessler I.
In vivo release of non-neuronal acetylcholine from the human skin as measured by dermal microdialysis: effect of botulinum toxin.
Br J Pharmacol. 2005 Nov 7;  

Thompson CS, Holowatz LA, Kenney WL.
Attenuated noradrenergic sensitivity during local cooling in aged human skin.
J Physiol. 2005 Apr 1;564(Pt 1):313-9.

Wong BJ, Tublitz NJ, Minson CT.
NEUROKININ-1 RECEPTOR DESENSITIZATION TO CONSECUTIVE MICRODIALYSIS INFUSIONS OF SUBSTANCE P IN HUMAN SKIN.
J Physiol. 2005 Aug 25;

Boutsiouki P, Georgiou S, Clough GF.
Recovery of Nitric Oxide from Acetylcholine-Mediated Vasodilatation in Human Skin In Vivo.
Microcirculation. 2004;11(3):249-259.

Eisenbarth H, Rukwied R, Petersen M, Schmelz M.
Sensitization to bradykinin B1 and B2 receptor activation in UV-B irradiated human skin.
Pain. 2004 Jul;110(1-2):197-204.  

Leis S, Drenkhahn S, Schick C, Arnolt C, Schmelz M, Birklein F, Bickel A.
Catecholamine release in human skin-a microdialysis study.
Exp Neurol. 2004 Jul;188(1):86-93.

Thompson CS, Kenney WL.
Altered neurotransmitter control of reflex vasoconstriction in aged human skin.
J Physiol. 2004 Jul 15;558(Pt 2):697-704. Epub 2004 Jun 04.

Cunningham DD, Young DF.
Measurements of glucose on the skin surface, in stratum corneum and in transcutaneous extracts: implications for physiological sampling.
Clin Chem Lab Med. 2003 Sep;41(9):1224-8.  

Kellogg DL Jr, Liu Y, McAllister K, Friel C, Pergola PE.
Bradykinin does not mediate cutaneous active vasodilation during heat stress in humans.
J Appl Physiol. 2002 Oct;93(4):1215-21.  

Shibasaki M, Wilson TE, Cui J, Crandall CG.
Acetylcholine released from cholinergic nerves contributes to cutaneous vasodilation during heat stress.
J Appl Physiol. 2002 Dec;93(6):1947-51

Cole ZA, Clough GF, Church MK
Dermatopharmacology Unit, Allergy and Inflammation Sciences, South Block 825, Southampton General Hospital, Southampton SO16 6YD.
Inhibition by glucocorticoids of the mast cell-dependent weal and flare response in human skin in vivo
Br J Pharmacol 2001 Jan 1;132(1):286-292  

Kellogg DL Jr, Liu Y, Pergola PE.
Selected contribution: Gender differences in the endothelin-B receptor contribution to basal cutaneous vascular tone in humans.
J Appl Physiol. 2001 Nov;91(5):2407-11; discussion 2389-90.

Koppert W, Blunk JA, Petersen LJ, Skov P, Rentsch K, Schmelz M.
Different patterns of mast cell activation by muscle relaxants in human skin.
Anesthesiology. 2001 Sep;95(3):659-67.

Schnetz E, Fartasch M.
Department of Dermatology, University of Erlangen, Hartmannstr 14, 91052, Erlangen, Germany
Microdialysis for the evaluation of penetration through the human skin barrier - a promising tool for future research?
Eur J Pharm Sci. 2001 Jan 20;12(3):165-174

Boelsma E, Anderson C, Karlsson AM, Ponec M.
Microdialysis technique as a method to study the percutaneous penetration of methyl nicotinate through excised human skin, reconstructed epidermis, and human skin in vivo.
Pharm Res. 2000 Feb;17(2):141-7.  

Shastry S, Minson CT, Wilson SA, Dietz NM, Joyner MJ.
Effects of atropine and L-NAME on cutaneous blood flow during body heating in humans.
J Appl Physiol. 2000 Feb;88(2):467-72.

Weidner C, Klede M, Rukwied R, Lischetzki G, Neisius U, Skov PS, Petersen LJ, Schmelz M.
Acute Effects of Substance P and Calcitonin Gene-Related Peptide in Human Skin - A Microdialysis Study.
J Invest Dermatol. 2000 Dec;115(6):1015-1020.

Benfeldt E, Serup J, Menne T.
Effect of barrier perturbation on cutaneous salicylic acid penetration in human skin: in vivo pharmacokinetics using microdialysis and non-invasive quantification of barrier function.
Br J Dermatol. 1999 Apr;140(4):739-48. 

Benfeldt E.
In vivo microdialysis for the investigation of drug levels in the dermis and the effect of barrier perturbation on cutaneous drug penetration. Studies in hairless rats and human subjects.
Acta Derm Venereol Suppl (Stockh). 1999;206:1-59.

Borg N, Gotharson E, Benfeldt E, Groth L, Stahle L.
Distribution to the skin of penciclovir after oral famciclovir administration in healthy volunteers: comparison of the suction blister technique and cutaneous microdialysis.
Acta Derm Venereol. 1999 Jul;79(4):274-7

Church MK, Clough GF.
Human skin mast cells: in vitro and in vivo studies.
Ann Allergy Asthma Immunol. 1999 Nov;83(5):471-5. Review

Clough G.
Experimental models of skin inflammation.
Clin Exp Allergy. 1999 Jul;29 Suppl 3:105-8. Review.

Krogstad AL, Lonnroth P, Larson G, Wallin BG.
Capsaicin treatment induces histamine release and perfusion changes in psoriatic skin.
Br J Dermatol. 1999 Jul;141(1):87-93.

Petersen LJ, Church MK, Rihoux JP, Skov PS.
Measurement of interstitial cetirizine concentrations in human skin: correlation of drug levels with inhibition of histamine-induced skin responses.
Allergy. 1999 Jun;54(6):607-11.  

Clough GF, Bennett AR, Church MK
Measurement of nitric oxide concentration in human skin in vivo using dermal microdialysis.
Exp Physiol 1998 May 83:3 431-4

Clough GF, Bennett AR, Church MK
Effects of H1 antagonists on the cutaneous vascular response to histamine and bradykinin: a study using scanning laser Doppler imaging.
Br J Dermatol 1998 May 138:5 806-14

Cross SE, Anderson C, Roberts MS
Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies.
Br J Clin Pharmacol 1998 Jul 46:1 29-35

Groth L
Cutaneous microdialysis. A new technique for the assessment of skin penetration.
Curr Probl Dermatol 1998 26: 90-8

Groth L, Serup J
Cutaneous microdialysis in man: effects of needle insertion trauma and anaesthesia on skin perfusion, erythema and skin thickness.
Acta Derm Venereol 1998 Jan 78:1 5-9  

Kellogg DL Jr, Crandall CG, Liu Y, Charkoudian N, Johnson JM
Nitric oxide and cutaneous active vasodilation during heat stress in humans.
J Appl Physiol 1998 Sep 85:3 824-9

M.Müller, C.Rastelli, P.Ferri, B.Jansen, H.Breiteneder, HG.Eichler.
Transdermal penetration of diclofenac following multiple epicutaneous administration.
J Rheumatology 25:1833-1837 (1998)

Petersen LJ
Measurement of histamine release in intact human skin by microdialysis technique. Clinical and experimental findings.
Dan Med Bull 1998 Sep 45:4 383-401

Church MK, Bewly AP, Clough GF, Burrows LJ, Ferdinand SI, Petersen LJ.
Studies into the mechanisms of dermal inflammation using cutaneous
microdialysis.
Int Arch Allergy Immunol 1997;113:131-3

Church MK
Reprint Available From: Church Mk Southampton Gen Hosp Clin Pharmacol Grp Tremona Rd Southampton So16 6yd Hants England
Investigating bradykinin-induced reactions in the skin through microdialysis.
Clinical & Experimental Allergy 1997 Nov;27(Suppl 2):28-32.

Petersen LJ, Church MK, Skov PS
Reprint Available From: Petersen Lj Bispebjerg Hosp Dept Dermatol Dk-2400 Copenhagen Denmark Natl Univ Hosp Reference Lab Copenhagen Denmark Southampton Gen Hosp Immunopharmacol Grp Southampton So9 4xy Hants England
Histamine is released in the wheal but not the flare following challenge of human skin in vivo - a microdialysis study.
Clinical & Experimental Allergy 1997 Mar;27(3):284-95.  

Petersen LJ
Reprint Available From: Petersen Lj Vildrosevej 30 Dk-3060 Espergerde Denmark Univ Copenhagen Bispebjerg Hosp Dept Dermatol Copenhagen Denmark
Quantitative measurement of extracellular histamine concentrations in intact human skin in vivo by the microdialysis technique - methodological aspects.
Allergy 1997 May;52(5):547-55.

Petersen LJ, Church MK, Skov PS
Reprint Available From: Petersen Lj Univ Copenhagen Bispebjerg Hosp Dept Dermatol Dk-2400 Copenhagen Nv Denmark Reference Lab Copenhagen Denmark Southampton Gen Hosp Immunopharmacol Grp Southampton So9 4xy Hants England
Platelet-activating factor induces histamine release from human skin mast cells in vivo, which is reduced by local nerve blockade.
Journal of Allergy & Clinical Immunology 1997 May;99(5):640-7.

Petersen LJ, Winge K, Brodin E, Skov PS
Reprint Available From: Petersen Lj Vildrosevej 30 Dk-3060 Espergerde Denmark Univ Copenhagen Bispebjerg Hosp Dept Dermatol Dk-1168 Copenhagen Denmark Reference Lab Copenhagen Denmark Karolinska Inst Dept Physiol & Pharmacol Stockholm Sweden
No release of histamine and substance p in capsaicin-induced neurogenic inflammation in intact human skin in vivo - a microdialysis study.
Clinical & Experimental Allergy 1997 Aug;27(8):957-65.

Anderson C, Andersson T, Boman A, Molander M
Department of Dermatology, University Hospital, Linkoping, Sweden.
Cutaneous microdialysis for the measurement in vivo of the
percutaneous absorption of organic solvents.
percutaneous absorption of organic solvents.
Curr-Probl-Dermatol 1996;25:37-46.

Groth L
Leo Pharmaceutical Products, Department of Dermatological Research, Ballerup, Denmark.
Cutaneous microdialysis. Methodology and validation.
Acta-Derm-Venereol-Suppl-Stockh 1996;197:1-61.

Horsmanheimo L, Harvima IT, Harvima RJ, Ylonen J, Naukkarinen A, Horsmanheimo M
Department of Dermatology, University of Kuopio, Finland.
Histamine release in skin monitored with the microdialysis technique does not correlate with the weal size induced by cow allergen.
Br-J-Dermatol 1996 Jan;134(1):94-100 

Horsmanheimo L, Harvima IT, Harvima RJ, Brummerkorvenkontio H, Francois G, Reunala T
Reprint Available From: Reunala T Helsinki Univ Hosp Dept Dermatol Fin-00250 Helsinki Finland Helsinki Univ Hosp Dept Dermatol Fin-00250 Helsinki Finland Kuopio Univ Hosp Dept Dermatol Sf-70210 Kuopio Finland Natl Publ Hlth Inst Helsinki Finland Inst Trop Med Prince Leopold Lab Protozool B-2000 Antwerp Belgium
Histamine and leukotriene c-4 release in cutaneous mosquito-bite reactions.
Journal of Allergy & Clinical Immunology 1996 Aug;98(2):408-11.

Huttunen M, Harvima IT, Ackermann L, Harvima RJ, Naukkarinen A, Horsmanheimo M
Department of Dermatology, Kuopio University Hospital, Finland.
Neuropeptide- and capsaicin-induced histamine release in skin monitored with the microdialysis technique.

Jansson PA, Krogstad AL, Lonnroth P
Reprint Available From: Jansson Pa Sahlgrens Univ Hosp Dept Internal Med Lundberg Lab Diabet Res S-41345 Gothenburg Sweden Sahlgrens Univ Hosp Dept Dermatol S-41345 Gothenburg Sweden
Microdialysis measurements in skin - evidence for significant lactate release in healthy humans.
American Journal of Physiology - Endocrinology & Metabolism 1996 Jul;34(1):E 138-E 142.
Acta-Derm-Venereol 1996 May;76(3):205-9.

Perzanowska M, Malhotra D, Skinner SP, Rihoux JP, Bewley AP, Petersen LJ, Church MK
Immunopharmacology Group, Southampton General Hospital, UK.
The effect of cetirizine and loratadine on codeine-induced histamine release in human skin in vivo assessed by cutaneous microdialysis.
Inflamm-Res 1996 Sep;45(9):486-90.

Petersen LJ, Mosbech H, Skov PS
Department of Dermatology, Bispebjerg Hospital, Copenhagen NV, Denmark.
Allergen-induced histamine release in intact human skin in vivo assessed by skin microdialysis technique: characterization of factors influencing histamine releasability.
J-Allergy-Clin-Immunol 1996 Feb;97(2):672-9

Petersen LJ, Brasso K, Pryds M, Skov PS
Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.
Histamine release in intact human skin by monocyte chemoattractant factor-1, RANTES, macrophage inflammatory protein-1 alpha, stem cell factor, anti-IgE, and codeine as determined by an ex vivo skin microdialysis technique.
J-Allergy-Clin-Immunol 1996 Oct;98(4):790-6.

Andersson T, Wardell K, Anderson C
Department of Dermatology, University Hospital, Linkoping, Sweden.
Human in vivo cutaneous microdialysis: estimation of histamine release in cold urticaria.
Acta-Derm-Venereol 1995 Sep;75(5):343-7.

Church MK, Skinner SP, Burrows LJ, Bewley AP.
Microdialysis in human skin [editorial].   

Hegemann L, Forstinger C, Partsch B, Lagler I, Krotz S, Wolff K
Department of Dermatology, University of Vienna, Austria.
Microdialysis in cutaneous pharmacology: kinetic analysis of transdermally delivered nicotine.
J-Invest-Dermatol 1995 May;104(5):839-43.

Okahara K, Murakami T, Yamamoto S, Yata N
Department of Biopharmaceutics, Hiroshima University School of Medicine, Japan.
Skin microdialysis: detection of in vivo histamine release in cutaneous allergic reactions.
Skin-Pharmacol 1995;8(3):113-8.  

Petersen LJ.
Skin microdialysis.
In Serup J, Jemec GBE (eds) Handbook of
Non-Invasive Methods and the Skin. CRC Press, Florida, USA. 1995, 607-18

Petersen LJ, Nielsen HJ, Skov PS
Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.
Codeine-induced histamine release in intact human skin monitored by skin microdialysis technique: comparison of intradermal injections with an atraumatic intraprobe drug delivery system.
Clin-Exp-Allergy 1995 Nov;25(11):1045-52.

Petersen LJ, Skov PS
Department of Dermatology, University of Copenhagen, Denmark.
Methacholine induces wheal-and-flare reactions in human skin but does not release histamine in vivo as assessed by the skin microdialysis technique.
Allergy 1995 Dec;50(12):976-80.

Anderson C, Andersson T, Wardell K
Department of Dermatology, University Hospital, Linkoping, Sweden.
Changes in skin circulation after insertion of a microdialysis
probe visualized by laser Doppler perfusion imaging.
J-Invest-Dermatol 1994 May;102(5):807-11.  

Petersen LJ, Poulsen LK, Sondergaard J, Skov PS
Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Denmark.
The use of cutaneous microdialysis to measure substance P-induced histamine release in intact human skin in vivo.
J-Allergy-Clin-Immunol 1994 Oct;94(4):773-83.

De Boer J, Plijter Groendijk H, Korf J
Department of Biological Psychiatry, University Hospital Groningen, The Netherlands.
Microdialysis probe for transcutaneous monitoring of ethanol and glucose in humans.
J-Appl-Physiol 1993 Dec;75(6):2825-30.  

Anderson C, Andersson T, Andersson RG
Department of Dermatology, University Hospital, Linkoping, Sweden.
In vivo microdialysis estimation of histamine in human skin.
Skin-Pharmacol 1992;5(3):177-83.  

Petersen LJ, Kristensen JK, Bulow J
Department of Clinical Physiology, Bispebjerg University Hospital, Copenhagen, Denmark.
Microdialysis of the interstitial water space in human skin in vivo: quantitative measurement of cutaneous glucose concentrations.
J-Invest-Dermatol 1992 Sep;99(3):357-60.

Petersen LJ, Skov PS, Bindslev Jensen C, Sondergaard J
Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.
Histamine release in immediate-type hypersensitivity reactions in intact human skin measured by microdialysis. A preliminary study.
Allergy 1992 Dec;47(6):635-7.