Bibliography Cardiac Monitoring
Relevant publications:
1. Lockowandt, U., Liska, J., Bäckström, T.& Franco-Cereceda, A. (2000)
Microdialysis of the cardiac venous outflow - a technique for monitoring myocardial ischemia. Scand Cardiovasc J, 34:1-6
2. Bäckström T, Lockowandt, U., Liska, C., Sylvén, C. & Franco-Cereceda, A. (2002).
Intravasal microdialysis for continuous monitoring of metabolites during myocardial ischemia and reperfusion. Scand Cardiovasc J 36:27-34.
3. Bäckström T, Goiny M., Lockowandt, U., Liska, J. & Franco-Cereceda, A. (2003).
Cardiac outflow of amino acids and purines during myocardial ischaemia and reperfusion.
J Appl Physiol 93;1122-1128.
4. Bäckström, T. & Franco-Cereceda, A. (2004).
Intravasal microdialysis is superior to intramyocardial microdalysis in detecting local ischemia in experimental porcine myocardial infarction. Acta Physiol Scand 179, 1-6.
5. Bäckström, T., Liska, J., Oldner, A., Lockowandt, U. & Franco-Cereceda, A. (2004). Splanchnic metabolism during gut ischemia, endotoxin shock and hemorrhagic shock evaluated by intravasal microdialysis. Shock, 21,572-578.
6. Bäckström T., Liska, C., Samuelsson, S. & Franco-Cereceda, A. (2007). Intravasal microdialysis as a monitoring tool in high-risk patients undergoing cardiac surgery. Scand Cardiovasc J; submitted;
7. Pöling, J., Rees, W., Klaus, S., Bahlmann, L., Hubners, N., Mantovani, V. and Warnecke, H. (2007). Myocardial metabolic monitoring with the microdialysis technique during and after open heart surgery. Acta Anaesthesiol Scand, 51, 341–346.
8. Mantovani V, Kennergren C, Goiny M, Ungerstedt U, Lönnroth P, Sala A and Berglin E. (2006) Microdialysis for myocardial metabolic surveillance: developing a clinical technique. Clin Physiol Funct Imaging, 26, 224–231.
Dissertation:
Bäckström, T. (2003). Intravasal microdialysis as a novel technique to monitor metabolism in myocardial ischemia and critical illness. ISBN 91-7349-534-4. Karolinska Institutet.
Conclusions from the above publications
• Intravascular catheters placed in the venous outflow of the heart can be used for continuous monitoring of chemical substances derived from the heart muscles metabolism. The catheters can also detect decreased oxygenation within 2 minutes (publications 1-3).
• The method can quickly detect changes that lead to infarcts and/or an ongoing lack of oxygenation. (publications 2-4)
• The chemical changes of analyzed metabolites precede signs of worsened pump function, hence it’s possible to detect early signs of circulatory failure by continuous monitoring metabolites deriving from the heart muscle. (publications 2, 4)
• Intravasal Microdialysis can monitor decease processes from other organs than heart such as in the gastrointestinal tract by analyzing substances from the venous flow. (publication 5)
• Intravasal Microdialysis more accurately reflect true changes in the metabolic status of an organ compared to tissue Microdialysis (publication 4-5)
• Intravasal Microdialysis has a potential for use in continuous postoperative control of patients subjected to cardiac surgery. (publication 6)