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CMA 66 Linear Microdialysis Catheter

   

 

    Approved for use in skin, adipose and resting
     skeletal muscle tissue

 

    Available with 20 kD or 100 kD cut-off

 

 Product note (pdf)        

                                                                                                      
CMA 66 Linear Microdialysis Catheter

 
Catheters inserted in skin
   

The CMA 66 Linear Microdialysis Catheter is a minimally invasive sterile single use device intended for Microdialysis monitoring in skin, adipose or resting skeletal muscle tissue. It has a new robust design with a high performance membrane.

The catheter is available with 20,000 or 100,000 Daltons cut off membrane. CMA 66 is suitable for many applications due to the linear design and the choice of low or high cut off membranes. It can be used for metabolic research, estimating the free fraction of a drug, pharmacokinetic and pharmacodynamic studies or monitoring inflammatory processes in vivo.

Insertion into the tissue is easily done with the help of a small needle introducer. The unique patented linear design makes the catheter robust and safe to use for several days. The two different dialyzing membranes have excellent diffusion characteristics, allowing a high recovery of substances in the extra cellular fluid. When using the high cut off membrane we recommend to perfuse the catheter with perfusion fluid containing high molecular weight substances for fluid balance and to avoid ultra filtration (e.g 30g Dextran 60/ 1000mL).

The catheter is connected to a CMA Microdialysis Pump and samples are regularly collected. The new design gives the opportunity to collect samples in both plastic and glass micro vials. The samples can be analyzed in the Microdialysis Analyzer for Glucose, Lactate, Pyruvate, Glutamate, Glycerol and Urea or sent to the clinical laboratory for various analyses by methods such as ELISA or HPLC.

Technical information for CMA 66

 
Membrane Cut-off: Approx. 20,000 Daltons or 100,000 Daltons 
Material Length (mm)
8010670/8010671
Length (mm)
8010650/8010651
Diameter
(mm)
Membrane PAES *   10   30 0.50
Inlet Tubing Polyurethane 400 400 0.38 
Outlet Tubing Polyurethane 100 100 0.38 
 Total length   510 530  
* PAES = Polyarylethersulphone 

Ordering information  for CMA 66

   
NOTE: This product may not be approved by your national regulatory authorities.
Please contact your local CMA representative for further information.

Ref. No.
8010650
CMA 66 Linear Catheter, 30mm 20kD (4/pkg) incl. Needle introducer
8010651 CMA 66 High Cut Off Linear Catheter, 30mm, 100kD (4/pkg) incl. Needle introducer
8010670 CMA 66 Linear Catheter, 10mm, 20kD (4/pkg) incl. Needle introducer
8010671 CMA 66 High Cut Off Linear Catheter, 10mm, 100kD (4/pkg) incl. Needle introducer

Accessories:
P000001
Microvials
P000028 Microvials in Rack
P000154 Microvials in Rack Sterile